Midtown Manhattan, or simply Midtown, is an area of Manhattan, New York City home to world-famous commercial zones such as Rockefeller Center, Broadway, and Times Square. Midtown Manhattan is home to the city's tallest and most famous buildings such as the Empire State Building and Chrysler Building.

Midtown, along with "Uptown" and "Downtown", is one of the three major subdivisions of Manhattan (though "Uptown" and "Downtown" can also be used as adjectives or prepositions, and can take on completely different meanings in the other boroughs, whereas the term "Midtown" cannot) and can be understood as those parts of Manhattan in neither of these two other regions - that is, all areas between14th Street and 59th Street, from the Hudson River to the East River, about five square miles or 12 km.